“Trials that take into account patients’ day-to-day concerns were once a rarity, but increasingly researchers are mulling trial designs that incorporate not only “hard” clinical endpoints, but also less tangible factors such as quality of life, time off work, expenses paid out of pocket, and the load borne by caregivers.”
Visit Website“Though there are signs that the increase in obesity rates is slowing in the United States, the proportion of adults and young people who are obese remains at an all-time high, according to the latest government data.”
Visit Website“Anacetrapib, the only cholesteryl ester transfer protein (CETP) inhibitor to modestly succeed in large-scale clinical trial testing, will not make it to market after all.”
Visit Website“When the Watchman left atrial appendage (LAA) closure device (Boston Scientific) came on the market, the number of complications reported to the US Food and Drug Administration (FDA) shot up initially but then started to come back down, a new analysis shows.”
Visit Website“Another retrospective analysis suggests that compared with the standard CABG practice of using the left internal thoracic artery (LITA) supplemented by saphenous vein grafts, multiple arterial grafting is associated with long-term survival and morbidity advantages.”
Visit Website“A task force from the European Society of Cardiology (ESC) and European Association of Percutaneous Cardiovascular Interventions (EAPCI) is now providing physicians with updated guidance on the use of bioresorbable scaffolds (BRS) in clinical practice, ultimately stating the devices have no role over drug-eluting stents”
Visit Website“Female and male surgeons achieve similar surgical outcomes, including complication and hospital readmission rates, but women come out a little bit ahead by virtue of offering a 12% relative reduction in 30-day mortality for their patients.”
Visit Website“There’s more evidence that patients with chronic kidney disease (CKD) fare worse following TAVR, this time from a large US database of more than 42,000 patients treated between 2011 and 2014.”
Visit Website“There’s an interplay between obesity and atrial fibrillation that will become ever more meaningful with the two conditions now reaching epidemic proportions, authors of a new review assert.”
Visit Website“US federal appeals court has vacated a permanent injunction that had banned Sanofi and its partner Regeneron from selling alirocumab (Praluent) in the United States and ordered a new trial to settle the dispute between Amgen and Sanofi/Regeneron over patents related to the development of their pricey PCSK9 inhibitors.”
Visit Website