Novel Application of Milrinone in the Evaluation of Classical Low-Flow, Low-Gradient Aortic Stenosis
In LFLG AS, because of the presence of a low-flow state, peak aortic jet velocity and MPG may underrate the AS severity. In contrast, AVA may overrate the severity of valvular stenosis because of inadequate opening of valve leaflets resulting from a reduced stroke volume. Valvular heart disease guidelines recommend that true-severe AS and pseudo-severe AS be distinguished by performing low-dose DSE in patients with classical LFLG AS.