In interventional cardiology and radiology, contrast media is a chemical substance used to enhance visualization of blood vessels and structures in medical imaging. The contrast medium or agent enhances the contrast of fluids or structures in the body. There are two types of contrast media used in angiography, iodine-based and Gadolinium-based.
Iodinated contrast agents are further divided into two categories: Ionic (high osmolar) and Non-ionic (low osmolar). Ionic contrast agents are less expensive and have been associated with an increased heat sensation, pain and cardiovascular changes when compared to non-ionic agents. Low osmolar agents are typically used in high-risk situations (nephrotoxicity) or when comfort of the patient is a special factor. They are also associated with a lower frequency of adverse drug reactions, and are considerably more expensive than their ionic counterpart.
Manufacturers / Products
- Omnipaque (iohexol Injection)
- Visipaque (iodixanol Injection)